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At GLP-1R and GIPR, EC50 values for cAMP accumulation are in the low nanomolar to picomolar range

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Interestingly, when transferring iNOS deficient (Nos2 -/- ) or wild-type bone marrow cells into irradiated recipient mice followed by Lewis lung carcinoma establishment, mice reconstituted with NOS2-deficient bone marrow cells had fewer M1 and similar numbers of M2 macrophages than mice reconstituted with bone marrow from wild-type mice

It provides a long-acting tool for investigating amylin's role in energy homeostasis